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Jumat, 14 Februari 2014

[H646.Ebook] Fee Download Principles of Pharmacogenetics and PharmacogenomicsFrom Cambridge University Press

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The study of pharmacogenetics and pharmacogenomics focuses on how our genes and complex gene systems influence our response to drugs. Recent progress in the science of clinical therapeutics has led to the discovery of new biomarkers that make it technically easier to identify groups of patients which are more or less likely to respond to individual therapies. The aim is to improve personalised medicine - not simply to prescribe the right medicine, but to deliver the right drug at the right dose at the right time. This textbook brings together contributions from leading experts to discuss the latest information on how human genetics impacts drug response phenotypes. It presents not only the basic principles of pharmacogenetics, but also clinically valuable examples that cover a broad range of specialties and therapeutic areas. The first section of the book outlines critical concepts in pharmacogenetics and pharmacogenomics, including genetic testing, genotyping technologies, and adverse drug effects. The next section discusses the legal, ethical, and social implications of pharmacogenomics. The second half of the book details many of the main therapeutic areas, including oncologic drugs, cardiovascular drugs, statins, drug-induced long QT syndrome, diabetes drugs, respiratory drugs, gastrointestinal drugs, rheumatoid arthritis drugs, obstetric drugs, psychiatric drugs, pain and anesthesia drugs, HIV and antiretroviral drugs, pediatrics, and fetal and neonatal medicine. This textbook is an invaluable introduction to pharmacogenetics and pharmacogenomics for health care professionals, medical students, pharmacy students, graduate students and researchers in the biosciences. RESOURCES @ www.cambridge.org/altman • Link to the Pharmacogenomics Knowledgebase • study guides • images from the book • discussion questions • content updates.

Sales Rank: #1286025 in Books
Published on: 2012-01-23
Original language: English
Number of items: 1
Dimensions: 9.96" h x .67" w x 6.97" l, 1.85 pounds
Binding: Hardcover
282 pages

About the Author
Russ Altman is Chairman of the Bioengineering Department and Professor of Bioengineering, Genetics, and Medicine at Stanford University. His primary research interests are in the application of computing technology to basic molecular biological problems of relevance to medicine.

David Flockhart is the Harry and Edith Gladstein Chair in Cancer Genomics and Professor of Medicine, Medical Genetics and Pharmacology at the Indiana University School of Medicine in Indianapolis. He is also the Director of the Division of Clinical Pharmacology. His research is focused on clinically relevant applications of pharmacogenetics and drug interactions.

David Goldstein is the Richard and Pat Johnson Distinguished University Professor and Director of the Center for Human Genome Variation at Duke University. He is also Professor of Molecular Genetics and Microbiology at Duke. His principal interests include human genetic diversity, the genetics of disease and pharmacogenetics.

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0 of 0 people found the following review helpful.
Five Stars
By MAHER AL-GHABRA
Great Book must have and Read

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Kamis, 13 Februari 2014

[T424.Ebook] PDF Ebook Wallace Stevens: The Poems of Our Climate, by Harold Bloom

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This dazzling book is at once an indispensable guide to Stevens's poetic canon and a significant addition to the literature on the American Romantic movement. It gives authoritative readings of the major long poems and sequences of Stevens and deals at length with the important shorter works as well, showing their complex relations both to one another and to the work of Stevens's precursors, Wordsworth, Shelley, Keats, Emerson, and Whitman. No other book on Stevens is as ambitious or comprehensive as this one: everyone who writes on Stevens will have to take it into account. The product of twenty years of meditating, thinking, and writing about Stevens, this truly remarkable book is a brilliant extension of Bloom's theories of literary interpretation.

Sales Rank: #597193 in Books
Published on: 1980-05-31
Original language: English
Number of items: 1
Dimensions: 9.28" h x 1.10" w x 6.04" l, 1.42 pounds
Binding: Paperback
416 pages

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22 of 25 people found the following review helpful.
The Bloom is Off the Prose
By Jeffrey Teich
Those of us who have bathed in the dazzling light of Bloom's exegeses of the Shakespeare plays will find on display in this volume a more obscure side of the great critic. The reader encounters here an earlier edition of Bloom, one who now expresses himself in sometimes tortuous prose and unwieldy language, now bludgeons rather than dissects. This Bloom has not yet gained his sure footing in the sparse, pithy prose of his more recent works which reveal him to be a master interpreter. Still, there is much here to admire; for Bloom shows us Steven's pedigree with marvelous clarity. Beginning with Emerson and proceeding to Whitman, Dickinson, Harte and others, Bloom illuminates Steven's debt to the rich provender on which he drew. (My own acquaintance with Emerson had languished since high school , but I soon found myself reading Emerson's superb essay on Shakespeare and Whitman's Leaves of Grass with a new eye.) Bloom shows how 'the American religion', an atheistic blending of respect for individual rights, power, will, and fate found their firm expression in Emerson and travelled onward to inform the poetry which followed, especially Stevens'. Bloom shows us how the tropes of fate, death, mother, and the sea wind through the years as each poet in turn struggles to express a uniquely American sense of meaning. True enough, Bloom fiddles too much with the technical bits, but he gives us a place from which to view Stevens' work so that we can now grasp why, as Bloom says, he was the greatest American poet of the 20th century- and perhaps of any century. Such favorites as The Auroras of Autumn, The Man with the Blue Guitar, The Emperor of Ice Cream and a score of others shine for us in a new light. Best of all, the reader carries with him the secret knowledge that despite these early slips,Bloom's brilliance will only grow.

5 of 5 people found the following review helpful.
The agony and ecstasy of reading.
By Barry Smith
I check 3 stars because, forced to check something, there's no 2.5, and thought I should tilt upward, considering what poet we're talking about. Very learned book on Stevens, too learned I think, anyway so much so a layman like me should probably keep his mouth shut, but the pleasure and melancholy in reading Stevens' poems, how obsessed one can get reading them, the daunting level from which he speaks, his language and measure like a god's, and the difficulty is rewarded many times over, for one learns a little more, feels a little more, inches up to each poem a little more, at each rereading, which explains at least in part why we're expending the energy in writing and reading books about them, for his poems, especially in this case Sunday Morning, are the products of a truly great, epochal poet, that belongs in the canon more assuredly than most.

But Mr. Bloom, you speak as though you're having late coffee and oranges in a sunny chair, while I in darkness cry out, please help me, how can I keep reading your book when I read something like this on the very poem in question: "... I think it not accidental that Sunday Morning, with all its Wordsworthian, Keatsian, and even repressedly Whitmanian touches, should be Stevens' most Tennysonian poem..." You think it not "accidental"? Help! I think I'm drowning! Anxiety of influence? My God, someone throw me a life line! Do I have expend 2 lifetimes devoted to careful study on all these other poets before I can even make a hairline crack in the seal that holds back Stevens? Perhaps I do. Farewell then, I'm going under, there's nothing more for me here in this life, someone notify my children, for I thought I could read Stevens, but now I wonder if I can even walk down the street!

10 of 15 people found the following review helpful.
Bloom shows Stevens a fit member of the post-Whitman/Emerson tradition
By Bo K.
Harold Bloom is probably my favorite critic, and Stevens one of the only 20th century poets in English I can bear to read without becoming hopelessly bored by the belatedness of the work. Bloom's book here is a close reading of the standard shorter and longer works of Stevens, and in so doing, Bloom shows how Steven's language and metaphor place him in the line of such Romantic poets as Keats, SHelly, and then of course, and most importantly, Whitman and Emerson. Emerson of course wrote rather weak poetry but his conception of the poet and his call for an American bard remain so strong today that very few poets/writers have the cognitive strength to deal with him. Most American writers fall back into the trope of nostalgia and flight (courtesy of Brockdon Brown); Stevens wrestled with this too, but his work ultimately stands in the orphic tradition of American poetry founded by Emerson, and whose strongest exemplars are of course Whitman and probably the Pan-American Pablo Neruda.

My only criticism of this book is that a) it does not address the great late poem "Sail of Ulysses," which is one of the most Emersonian poems in Steven's canon; further, b), Bloom's tone in this book, as compared with most of his others about the Romantic tradition, is not quite so strident. Some don't like Bloom at when he is strident, but I love his work the more he sounds like a high-toned Christian preacher in his Emersonian pulpit. However, it may be that Bloom is unable to rise to such heights in this book because, as great as Stevens is, he never truly defeated his agon with Emerson and Whitman; he never truly overcame his belatedness. Stevens came very near to doing so in his best work, but I am sorry to say that I think Stevens remains an ephebe to Emerson and Whitman. That is not to reduce his achievement; very few poets are able to defeat their precursors. Stevens is a canonical poet without a doubt; however, when I then open Whitman or Neruda, I see that his voice is indeed quite a bit weaker than theirs. The little old lady from Des Moines will then say, "yes sir of course, but whose voices could ever be as strong as theirs?!" And I would say to her then hallelujah madame!

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Rabu, 12 Februari 2014

[S950.Ebook] Fee Download National Geographic Magazine, May 1978 (Vol. 153, No. 5), by National Geographic. (Robyn Davidson)

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Sales Rank: #1131313 in Books
Published on: 1978-05
Dimensions: 7.00" h x .50" w x 10.00" l,
Binding: Single Issue Magazine
149 pages

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0 of 0 people found the following review helpful.
May 1978
By Brice Clark
Super RARE Issue!

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[J417.Ebook] Fee Download The Wild Geese, by Ogai Mori

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Written in 1913, this modern classic was the source for the highly acclaimed film, The Mistress

In The Wild Geese, prominent Japanese novelist Ogai Mori offers a poignant story of unfulfilled love, set against the background of the dizzying social change accompanying the fall of the Meiji regime. The young heroine, Otama, is forced by poverty to become a moneylender's mistress. She is surrounded by skillfully-drawn characters—her weak-willed father, her virile and calculating lover (and his suspicious wife), and the handsome student who is both the object of her desire and the symbol of her rescue—as well as a colorful procession of Meiji era figures—geisha, students, entertainers, unscrupulous matchmakers, shopkeepers, and greedy landladies.

Like those around her, and like the wild geese of the titles, Otama yearns for the freedom of flight. Her dawning consciousness of her predicament brings the novel to a touching climax.

Sales Rank: #327370 in Books
Published on: 2009-07-10
Released on: 2009-07-10
Original language: English
Number of items: 1
Dimensions: 8.00" h x .50" w x 5.13" l, .35 pounds
Binding: Paperback
160 pages

Features

ISBN13: 9784805308844
Condition: New
Notes: BRAND NEW FROM PUBLISHER! 100% Satisfaction Guarantee. Tracking provided on most orders. Buy with Confidence! Millions of books sold!

Review
"The Wild Geese is a spare, yet intricate, read. The narrative moves quickly, and the characters are developed in a way that successfully reveals their passiveness and internal weaknesses. It is a good book that clearly has paved the path for later writers, and for those seeking the early inspiration for the great Japanese Masters that filled the 20th Century, Ogai Mori is not a writer to overlook." —BlogCritics.com

About the Author
Ogai Mori (1862-1922) stands in the foremost rank of modern Japanese novelists. His professional success as an army surgeon was outstripped by his even more brilliant ascent in the literary world of the Meiji and Taisho eras. His work is characterized by a strong humanistic element, a romantic quality effectively tempered by realism, and a lucid style that often rises to lyric intensity as in the closing passages of The Wild Geese. Written in 1913, The Wild Geese enjoyed such success in Japan that it was made into a film, shown abroad as The Mistress.

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0 of 0 people found the following review helpful.
I am so happy to have found the book that my great-uncles were ...
By SIWA
I am so happy to have found the book that my great-uncles were reading when they came up with my grandmother's name. Grandma gave the name to my mother, I took it for myself (I liked it so much) and then gave it to my daughter. I just love having the story I heard all my life come to reality.

3 of 3 people found the following review helpful.
Achingly beautiful
By The Reviewer Formerly Known as Kurt Johnson
This is a tale of complex people who in their interaction find life to be much more complicated than they had expected or feared. Suezo, a moneylender, is tired of life with his nagging, highly imperfect wife, so he decides to take a mistress. Otama, the only child of a widower merchant, wishes that she could provide for her aging father, and when an obviously rich man asks her to be his mistress, a new hope beckons. When Otama learns the truth about Suezo, she feels betrayed, and hopes to find a hero to rescue her. When Otama meets Okada, a medical student, she feels that she might indeed have met her hero.

This is a bittersweet story, a story of hope and unfairness. The wild geese wish only for freedom, but sometimes others use them for purposes they cannot imagine. Published between 1911 and 1913, this book gives an excellent peek into the society of early modern Japan.

This book is an achingly beautiful story, and a fascinating historical document. I highly recommend it.

8 of 12 people found the following review helpful.
The coflict between love and surperstition!!
By koske kawasaki
This love story of a girl who became a lover of an old bill collecter and fall in love with a medical student is a sign of japanese mentality in the drastic changing situation between the periode "Edo" and periode "Meiji". As his first novel "Dancer"in wich he told his uncompleated love in Germany(at that time,having a foreign wife was a taboo), Mori tried to show the example of a conflict of natural feeling of love and the traditional superstition.Why the girl could not acheave her love? In Japan they said that a real love is a love forbidden, but it is sure that what Mori wanted to say in this book is not that beauty.

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Senin, 03 Februari 2014

[S885.Ebook] Ebook Download Adult Development and Aging, by John C. Cavanaugh, Fredda Blanchard-Fields

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Written within a bio-psychosocial framework, Cavanaugh and Blanchard-Fields' best-selling book covers the specific ages-stages of adult development and aging. In its unparalleled coverage of current research and theory, the authors draw clear connections between research and application. The book's focus on "positive aging" and the gains and losses people experience across adulthood distinguish it from its competitors.

Sales Rank: #7443 in Books
Published on: 2014-02-06
Original language: English
Number of items: 1
Dimensions: .30" h x 8.60" w x 10.40" l, .0 pounds
Binding: Hardcover
496 pages

About the Author
John C. Cavanaugh is President and CEO of the Consortium of Universities of the Washington Metropolitan Area. He received his undergraduate degree from the University of Delaware and his Ph.D. from the University of Notre Dame. Cavanaugh is a fellow of the American Psychological Association, the Association for Psychological Science, and the Gerontological Society of America, and has served as president of the Adult Development and Aging Division (Division 20) of the APA. Cavanaugh has also written (with the late Fredda Blanchard-Fields) ADULT DEVELOPMENT AND AGING. His research interests in gerontology concern family caregiving as well as the role of beliefs in older adults' cognitive performance.

Fredda Blanchard-Fields, Ph.D., is Professor of Psychology and Chair of the department at Georgia Institute of Technology. Her current research interests include social cognition in adulthood and aging as well as everyday problem solving and emotion regulation from adolescence through older adulthood. She has been published in Psychology and Aging, Developmental Psychology, Current Directions in Psychological Science, and other journals. She is a fellow of both the American Psychological Association and the Gerontological Society of America and a member of the American Psychological Society, the Society for Research and Child Development, and the Psychonomics Society.

Most helpful customer reviews

3 of 3 people found the following review helpful.
Not just for students!
By Alyssa Arnoldus
It is a text book, but any one who has an elderly parent needs to buy this book

2 of 2 people found the following review helpful.
Five Stars
By madison
Had to get this for a college class. It got the job done.

0 of 0 people found the following review helpful.
Great set up. Interesting and relevant content.
By Hannah Horspool
Of all the textbooks I purchased for my undergraduate degree, this is one of few that I actually read, almost in its entirety. I learned so much about aging from this book and my eyes were opened to many things I should take more seriously about my health and working with the elderly. I enjoyed the set up of each chapter--each chapter begins with real life examples of people related to the issues/concepts of the chapter.

It was required, but it was also very useful. I still sometimes wish that I had not sold it back at the end of the semester.

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[F172.Ebook] Download PDF Soil Microbiology, Ecology and Biochemistry, Fourth Edition, by Eldor A. Paul

Download PDF Soil Microbiology, Ecology and Biochemistry, Fourth Edition, by Eldor A. Paul

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Soil Microbiology, Ecology and Biochemistry, Fourth Edition, by Eldor A. Paul

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The fourth edition of Soil Microbiology, Ecology and Biochemistry updates this widely used reference as the study and understanding of soil biota, their function, and the dynamics of soil organic matter has been revolutionized by molecular and instrumental techniques, and information technology. Knowledge of soil microbiology, ecology and biochemistry is central to our understanding of organisms and their processes and interactions with their environment. In a time of great global change and increased emphasis on biodiversity and food security, soil microbiology and ecology has become an increasingly important topic.

Revised by a group of world-renowned authors in many institutions and disciplines, this work relates the breakthroughs in knowledge in this important field to its history as well as future applications. The new edition provides readable, practical, impactful information for its many applied and fundamental disciplines. Professionals turn to this text as a reference for fundamental knowledge in their field or to inform management practices.

New section on "Methods in Studying Soil Organic Matter Formation and Nutrient Dynamics" to balance the two successful chapters on microbial and physiological methodology
Includes expanded information on soil interactions with organisms involved in human and plant disease
Improved readability and integration for an ever-widening audience in his field
Integrated concepts related to soil biota, diversity, and function allow readers in multiple disciplines to understand the complex soil biota and their function

Sales Rank: #152385 in Books
Published on: 2014-11-27
Original language: English
Number of items: 1
Dimensions: 9.10" h x 1.30" w x 6.10" l, 2.50 pounds
Binding: Hardcover
598 pages

About the Author
Eldor A. Paul is a Senior Research Scientist at the Natural Resources Ecology Laboratory at Colorado State University, Fort Collins and Professor Emeritus at Michigan State University, East Lansing. During his time at Michigan State, he was professor of Soil Microbiology and Biochemistry, and Crop and Soil Sciences. He earned degrees from the University of Alberta and the University of Minnesota. His research focuses on the dynamics of soil organic matter and the microbial ecology of soil. Dr. Paul is a Fellow of ASA, SSSA, the Canadian Society of Soil Science, and the American Association for the Advancement of Science.

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0 of 0 people found the following review helpful.
One Star
By HUSSEINUNL
It is white and black. While my friend have got one with color ....

0 of 0 people found the following review helpful.
Five Stars
By Mark Rasmussen
Good book

0 of 1 people found the following review helpful.
Two Stars
By Steph Hays
The figures are tiny - this is not a book that works really well on a kindle.

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[W719.Ebook] Download Land Use, Environment, and Social Change: The Shaping of Island County, Washington (Weyerhaeuser Environmental Books (Paperback)), by Rich

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Whidbey and Camano, two of the largest of the numerous beautiful islands dotting Puget Sound, together form the major part of Island Country. Taking this county as a case study and following its history from Indian times to the present, Richard White explores the complex relationship between human induced environmental change and social change. This new edition of his classic study includes a new preface by the author and a foreword by William Cronon.

Sales Rank: #727678 in Books
Published on: 1999-06-01
Original language: English
Number of items: 1
Dimensions: 9.02" h x .60" w x 5.98" l, .94 pounds
Binding: Paperback
246 pages

Review
"An example of environmental history at its best. . . . A fresh appraisal of human contact with the environment, with special attention to the apparent motives of each wave of settlement―Indians, farmers, loggers, tourists and sportsmen―and the consequences of that settlement."―Journal of the West

From the Back Cover
Whidbey and Camano, two of the largest of the numerous beautiful islands dotting Puget Sound, together form the major part of Island County. Taking this county as a case study and following its history from Indian times to the present, Richard White explores the complex relationship between human induced environmental change and social change. This new edition of his classic study includes a new preface by the author and a foreword by William Cronon.

Most helpful customer reviews

13 of 13 people found the following review helpful.
Classic of Environmental History
By A Customer
Over the past two decades, Richard White has been one of the truly outstanding historians of the American West, Native America, and the environment. This, his first book, is not nearly as sweeping in scope as his later works, but is a masterful look at the environmental history of a small county in Western Washington that will interest any student of American history. White examines the interaction of humans and the environment in Island County, Washington, to demonstrate how humans have continuously shaped the land over thousands of years, and how these changes have been both conscious and accidental. The opening chapters concern Indian land use in the county, and conclude that native people largely determined the region's landscape by encouraging certain crops through burning of prairies and forests. While this insight is fairly obvious to most environmental historians now, it is a direct contradiction of the European opinion that Indians did not alter the land. White settlers also altered the landscape of Island County by introducing market agriculture and logging. These activities had drastic consequences, some intentional, such as the introduction of European crops, and some unintentional, like massive soil erosion and the accidental spread of the Canadian thistle, a weed that temporarily threatened farmers in the nineteenth century. The final chapters of the book concern twentieth century attempts to encourage settlement of Appalachian farmers on logged-off land (a fascinating New Deal effort that was a complete failure), and the attempt to change the island landscape for the benefit of tourists. This is a fascinating transformation that continues to this day. Overall, this is a very well-written classic of environmental history. The in-depth descriptions of ecological principles may scare off a novice reader, but the history embedded in the ecology is fascinating, and well worth the effort.

0 of 0 people found the following review helpful.
A great introduction to human influences on the land and vice versa
By C
White takes a refreshingly sympathetic approach to talking about human influences on the land. He talks about both American Indians and white settlers that makes them seem real and relevant to today and gives them credit for being real, thinking people. A welcome change from many books.

1 of 2 people found the following review helpful.
it matters how we use the land
By C. Kollars
A couple decades ago a new style of research-and-resulting-book appeared. It told the story of land use from the point of view of a historian, including the mutual effect of geography and social organization. This book is one of them (another is Changes in the Land, Revised Edition: Indians, Colonists, and the Ecology of New England by William Cronon). Unfortunately nobody picked up the trend and it died out after an excellent start.

Revisiting these old gems is highly worthwhile. They shed light on the intersection of ecology and human populations. By following the same place for decades or even centuries, they show which kinds of human uses fit well into the given geography and which didn't.

Who knew that by studying Island County in detail you could find out that:
(1) Sustainable Indian population levels were actually *higher* than sustainable non-Indian population levels until quite recently.
(2) A political and social "back to the land" movement lasted several decades (even though there was very little evidence behind it), and caused a huge amount of human sorrow.
(3) Applying "standard" human use patterns to every different geography resulted in not just very disappointing returns but also permanent ecological damage.
(4) Seemingly very minor actions for just a few years (for example overgrazing) resulted in ecological changes that last so long they are essentially permanent.
(5) City-folks attitudes dramatically affected on country-folks ways of life.
(6) Agricultural over-population made life extremely difficult for the recent arrivals.

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